A functional GFP fusion for imaging clathrin-mediated endocytosis.
New York City, United States. In Traffic, 2008
In this study, we present the first demonstration that one of these proteins, in this case a green fluorescent protein (GFP) fusion to alpha-adaptin, a marker of the adaptor protein-2 complex, functionally complements knockdown of endogenous protein through small interfering RNA silencing.
Numb: "Adapting" notch for endocytosis.
Houston, United States. In Dev Cell, 2002
In this issue of Developmental Cell, Berdnik et al. show that Numb recruits alpha-Adaptin and that this physical interaction plays a role in downregulating Notch, presumably by stimulating endocytosis of Notch.