gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


Top mentioned proteins: p15, V1a, Dynamin I, Eps15, Transferrin
Papers on alpha-adaptin
Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells.
Lu et al., Stanford, United States. In J Biol Chem, 2012
Interaction of Notch signaling modulator Numb with alpha-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells.
Advanced glycation end products inhibit Na+ K+ ATPase in proximal tubule epithelial cells: role of cytosolic phospholipase A2alpha and phosphatidylinositol 4-phosphate 5-kinase gamma.
Bach et al., Australia. In Biochim Biophys Acta, 2010
AGE-BSA increased binding of NKA to the alpha-adaptin but not beta2- or mu2-adaptin subunits of the AP-2 clathrin pit adaptor complex.
Cardiac progenitor cell cycling stimulated by pim-1 kinase.
Sussman et al., San Diego, United States. In Circ Res, 2010
Localization and quantitation of cell fate determinants Numb and alpha-adaptin by confocal microscopy were used to assess frequency of asymmetric division in the CPC population.
HM1.24 is internalized from lipid rafts by clathrin-mediated endocytosis through interaction with alpha-adaptin.
Tanaka et al., Fukuoka, Japan. In J Biol Chem, 2009
Indeed, an appendage domain of alpha-adaptin was identified as a protein interacting with the cytoplasmic tail of HM1.24.
A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.
Bonifacino et al., Bethesda, United States. In J Virol, 2009
We also present evidence that the diacidic motif on Nef and the basic patch on alpha-adaptin are both required for the cooperative assembly of a CD4-Nef-AP-2 complex.
Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6.
Smythe et al., Sheffield, United Kingdom. In J Cell Biol, 2008
hRME-6 guanine nucleotide exchange factor activity requires hRME-6 binding to alpha-adaptin ear, which displaces the ear-associated mu2 kinase AAK1.
Intracellular peptides as natural regulators of cell signaling.
Ferro et al., São Paulo, Brazil. In J Biol Chem, 2008
Moreover, using individual peptides as baits in affinity columns, several proteins involved in GPCR signaling were identified, including alpha-adaptin A and dynamin 1.
A functional GFP fusion for imaging clathrin-mediated endocytosis.
Simon et al., New York City, United States. In Traffic, 2008
In this study, we present the first demonstration that one of these proteins, in this case a green fluorescent protein (GFP) fusion to alpha-adaptin, a marker of the adaptor protein-2 complex, functionally complements knockdown of endogenous protein through small interfering RNA silencing.
Sequence analysis of Arabidopsis thaliana E/ANTH-domain-containing proteins: membrane tethers of the clathrin-dependent vesicle budding machinery.
Oliviusson et al., Heidelberg, Germany. In Protoplasma, 2005
At-AP180 displays conserved functions as a clathrin assembly protein and as an alpha-adaptin binding partner, and in addition shows features at the molecular level that seem to be plant-specific.
Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs.
Knoblich et al., Vienna, Austria. In Embo Rep, 2005
Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs.
Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit.
Grant et al., United States. In Nat Cell Biol, 2005
However, unlike other Rab5-associated proteins, a rescuing green fluorescent protein (GFP)-RME-6 fusion protein primarily localizes to clathrin-coated pits, physically interacts with alpha-adaptin, a clathrin adaptor protein, and requires clathrin to achieve its cortical localization.
CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth.
Kaibuchi et al., Nagoya, Japan. In Nat Cell Biol, 2003
Numb has been shown to interact with alpha-adaptin and to be involved in endocytosis.
The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila.
Knoblich et al., Vienna, Austria. In Dev Cell, 2002
Numb polarizes the distribution of alpha-Adaptin, involved in receptor-mediated endocytosis. Alpha-Adaptin mutations not binding to Numb don't localize asymmetrically and cause defects in asymmetric cell division.
Numb: "Adapting" notch for endocytosis.
Bellen et al., Houston, United States. In Dev Cell, 2002
In this issue of Developmental Cell, Berdnik et al. show that Numb recruits alpha-Adaptin and that this physical interaction plays a role in downregulating Notch, presumably by stimulating endocytosis of Notch.
A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.
McMahon et al., Cambridge, United Kingdom. In Cell, 1999
The alpha subunit of the endocytotic AP2 adaptor complex contains a 30 kDa "appendage" domain, which is joined to the rest of the protein via a flexible linker.
Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.
De Camilli et al., New Haven, United States. In Nature, 1998
One of these factors is Eps15, a clathrin-coat-associated protein that binds the alpha-adaptin subunit of AP-2.
Role of Drosophila alpha-adaptin in presynaptic vesicle recycling.
Jäckle et al., Göttingen, Germany. In Cell, 1997
Rapid flow of information in the nervous system involves presynaptic vesicle recycling by clathrin-mediated endocytosis, an event triggered by the alpha-adaptin-containing AP2 complex.
Dynamin, a GTPase involved in the initial stages of endocytosis.
Shpetner et al., Shrewsbury, United States. In Ciba Found Symp, 1992
Overexpression of mutant forms of dynamin in vivo using Cos-7 cells inhibits transferrin uptake and alters the distribution of clathrin and of alpha-adaptin, but not gamma-adaptin.
share on facebooktweetadd +1mail to friends