Comparative proteome analysis of saccular intracranial aneurysms with iTRAQ quantitative proteomics.
Beijing, China. In J Proteomics, Feb 2016
Furthermore, Integrin β3, Secreted frizzled-related protein 2 were significantly up-regulated (2.3 fold and 2.1 fold, respectively), whereas MyosinIIb, Alpha-actinin-1, Laminin β2, and Carboxypeptidase A3 were down-regulated (3.01 fold, 2.1 fold, 2.07 fold, and 2.01 fold, respectively) in sIAs.
Update on the causes of platelet disorders and functional consequences.
Leuven, Belgium. In Int J Lab Hematol, 2014
A major step forward was made during the last 3 years using new-generation genetic approaches that resulted in the discovery of novel genes such as NBEAL2, RBM8A, ACTN1, and GFI1B for the well-known IPD that cause gray platelet syndrome, thrombocytopenia-absent radius syndrome, and autosomal dominant thrombocytopenias, respectively.
Alpha-actinin 4 and tumorigenesis of breast cancer.
Cleveland, United States. In Vitam Horm, 2012
Notably, unlike other ACTNs, alpha-actinin 4 (ACTN4) displays unique characteristics in signaling transduction, nuclear translocation, and gene expression regulation.
Competitive binding of alpha-actinin and calmodulin to the NMDA receptor.
Boston, United States. In Nature, 1997
alpha-Actinin-2, a member of the spectrin/dystrophin family of actin-binding proteins, is identified here as a brain postsynaptic density protein that colocalizes in dendritic spines with NMDA receptors and the putative NMDA receptor-clustering molecule PSD-95.