Papers on
alpha-Actinin
Comparative proteome analysis of saccular intracranial aneurysms with iTRAQ quantitative proteomics.Zhao et al., Beijing, China. In J Proteomics, Feb 2016
Furthermore, Integrin β3, Secreted frizzled-related protein 2 were significantly up-regulated (2.3 fold and 2.1 fold, respectively), whereas MyosinIIb, Alpha-actinin-1, Laminin β2, and Carboxypeptidase A3 were down-regulated (3.01 fold, 2.1 fold, 2.07 fold, and 2.01 fold, respectively) in sIAs.
Update on the causes of platelet disorders and functional consequences.van Geet et al., Leuven, Belgium. In Int J Lab Hematol, 2014
A major step forward was made during the last 3 years using new-generation genetic approaches that resulted in the discovery of novel genes such as NBEAL2, RBM8A, ACTN1, and GFI1B for the well-known IPD that cause gray platelet syndrome, thrombocytopenia-absent radius syndrome, and autosomal dominant thrombocytopenias, respectively.
Pathogenesis and management of inherited thrombocytopenias: rationale for the use of thrombopoietin-receptor agonists.Pecci, Pavia, Italy. In Int J Hematol, 2013
In the last 5 years, nine new genes whose mutations are responsible for thrombocytopenia have been identified, and this also led to the recognition of several novel nosographic entities, such as thrombocytopenias deriving from mutations in CYCS, TUBB1, FLNA, ITGA2B/ITGB3, ANKRD26 and ACTN1.
Alpha-actinin 4 and tumorigenesis of breast cancer.Kao et al., Cleveland, United States. In Vitam Horm, 2012
Notably, unlike other ACTNs, alpha-actinin 4 (ACTN4) displays unique characteristics in signaling transduction, nuclear translocation, and gene expression regulation.
Competitive binding of alpha-actinin and calmodulin to the NMDA receptor.Sheng et al., Boston, United States. In Nature, 1997
alpha-Actinin-2, a member of the spectrin/dystrophin family of actin-binding proteins, is identified here as a brain postsynaptic density protein that colocalizes in dendritic spines with NMDA receptors and the putative NMDA receptor-clustering molecule PSD-95.