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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ADRA2A adrenergic, alpha-2A-, receptor

alpha 2-adrenergic receptor, alpha 2D-adrenergic receptor
Top mentioned proteins: HAD, CAN, ACID, V1a, AGE
Papers on alpha 2-adrenergic receptor
Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury.
Ju et al., San Diego, United States. In Plos One, 2011
Brimonindine (BMD), an alpha 2-adrenergic receptor agonist, contributes to the neuroprotection of retinal ganglion cells (RGCs) against glutamate excitotoxicity or oxidative stress.
Antinociceptive and anti-inflammatory effects of octacosanol from the leaves of Sabicea grisea var. grisea in mice.
Barreto et al., MaceiĆ³, Brazil. In Int J Mol Sci, 2011
Pre-treatment with yohimbine, an alpha 2-adrenergic receptor antagonist, notably reversed the antinociceptive activity induced by octacosanol in the abdominal constriction test.
Protective mechanism of agmatine pretreatment on RGC-5 cells injured by oxidative stress.
Seong et al., Seoul, South Korea. In Braz J Med Biol Res, 2010
Cell viability was determined by measuring lactate dehydrogenase (LDH), and the effects of selective alpha 2-adrenergic receptor antagonist yohimbine (0-500 nM) and N-methyl-D-aspartic acid (NMDA) receptor agonist NMDA (0-100 microM) were evaluated.
Involvement of signaling pathways in bovine sperm motility, and effect of ergot alkaloids.
Rosenkrans et al., Fayetteville, United States. In In Vitro Cell Dev Biol Anim, 2009
Relative sperm motility (motility of treated spermatozoa normalized to control sperm motility) was increased (p < 0.05) when co-incubations included ET and yohimbine (alpha 2-adrenergic receptor inhibitor); conversely, co-incubation of yohimbine (100 microM) and DHET decreased (p < 0.05) the percentage of motile spermatozoa when compared with controls.
Clinical pharmacokinetics of lofexidine, the alpha 2-adrenergic receptor agonist, in opiate addicts plasma using a highly sensitive liquid chromatography tandem mass spectrometric analysis.
Al-Ghananeem et al., Philadelphia, United States. In Am J Drug Alcohol Abuse, 2007
Lofexidine is an orally bioavailable alpha 2-adrenergic receptor agonist analogue of clonidine that acts centrally to suppress opiate withdrawal symptoms.
[Metabolic and trophic role of catecholamines in the development of white adipose tissue].
Saulnier-Blache et al., Toulouse, France. In Ann Endocrinol (paris), 1999
Preadipocyte alpha 2-adrenergic receptor stimulation initiates proliferation mediated by MAPkinase activation and cytoskeleton re-arrangements.
Pharmacological approach to functional reorganization: the role of norepinephrine.
Goldstein, Durham, United States. In Rev Neurol (paris), 1998
Drugs that deplete central norepinephrine, block alpha 1-adrenergic receptors, or decrease norepinephrine release (alpha 2-adrenergic receptor agonists) impede recovery whereas drugs that increase norepinephrine release (alpha 2-adrenergic receptor antagonists) or sympathomimetics (amphetamine) facilitate recovery.
New approaches to rapid onset antidepressants.
Dodel et al., Indianapolis, United States. In Curr Pharm Des, 1998
These approaches include combinations of SSRI activity with either NA reuptake inhibition or 5-HT1A-, 5-HT2-, or alpha 2-adrenergic receptor specificity, as well as targeting interactions with specific receptor subtypes (5-HT1A, 5-HT1A/5-HT2, 5-HT1B/D, alpha 2/5-HT2, D2/D3).
Is the hypotensive effect of clonidine and related drugs due to imidazoline binding sites?
Guyenet, Charlottesville, United States. In Am J Physiol, 1997
Clonidine and related alpha 2-adrenergic receptor (alpha 2AR) agonists lower arterial pressure primarily by an action within the central nervous system.
[Molecular biology of alpha-adrenergic receptor and essential hypertension].
Yasuda et al., Yokohama, Japan. In Nihon Rinsho, 1993
In addition, the association analysis of alpha 2-adrenergic receptor gene RFLP in essential hypertension has been performed.
Functional restoration of the traumatically injured spinal cord in cats by clonidine.
Naftchi, In Science, 1982
The long-term, chronic, paralysis resulting from spinal cord injury in the cat has been reversed by the use of an alpha 2-adrenergic receptor agonist, clonidine.
Spinal sympathetic neurons: possible sites of opiate-withdrawal suppression by clonidine.
McCloskey et al., In Science, 1982
Naloxone promptly antagonized this effect of the opiates but not that of clonidine which was reversed by alpha 2-adrenergic receptor antagonists.
Differential regulation of the alpha 2-adrenergic receptor by Na+ and guanine nucleotides.
Lefkowitz et al., In Nature, 1981
We investigate here the effects of Na+ and guanine nucleotides on the adenylate cyclase-coupled inhibitory alpha 2-adrenergic receptor of the rabbit platelet.
alpha 2-Adrenergic receptors appear in rat salivary glands after reserpine treatment.
Martinez et al., In Nature, 1980
We have recently identified and characterised alpha 1-adrenergic receptors in the rat submandibular gland, but surprisingly, alpha 2-adrenergic receptor binding was not detectable.
beta-Adrenergic regulation of alpha 2-adrenergic receptors in the central nervous system.
Enna et al., In Science, 1980
Incubation of rat cerebral cortical slices with the beta-adrenergic agonist isoproterenol causes an increase in alpha 2-adrenergic receptor binding in addition to a decrease in beta-adrenergic receptor binding.
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