Alkaline Phosphatase and Hypophosphatasia.
Los Angeles, United States. In Calcif Tissue Int, Dec 2015
UNASSIGNED: Hypophosphatasia (HPP) results from ALPL mutations leading to deficient activity of the tissue-non-specific alkaline phosphatase isozyme (TNAP) and thereby extracellular accumulation of inorganic pyrophosphate (PPi), a natural substrate of TNAP and potent inhibitor of mineralization.
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
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Rochester, United States. In N Engl J Med, Oct 2015
Treatment-related adverse events included grade 4 thrombocytopenia (in 18% of patients), grade 4 neutropenia (in 12%), grade 3 anemia (in 30%), and grade 1 or 2 elevation in levels of total bilirubin (in 12%), alkaline phosphatase (in 21%), and aspartate aminotransferase (in 27%).
Heterogeneity and plasticity of T helper cells
In Scandinavian Journal of Immunology, 2009
... Streptavidin-alkaline phosphatase (SA-ALP) and BCIP/NBT (5-bromo-4-chloro-3-indolyl phosphate/nitro-blue tetrazolium) substrate were both from Mabtech as were anti-FITC-Green, Streptavidin-Red ... Prevention of mammary tumorigenesis by intermittent caloric restriction: does caloric intake during refeeding modulate the response?
In Breast Cancer Research : BCR, 2006
... antibodies against Ob, ObR, phosphorylated STAT3 (pSTAT3), Jak2, phosphorylated Akt (pAkt), Bcl-2, Bcl-xL, Bax, and alkaline phosphatase-conjugated goat anti-mouse immunoglobulin G (IgG) were purchased from Santa Cruz Biotechnology, Inc ...