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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Ephrin-A5

ALI, Ephrin-A5, AL-1
Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Interleukin-6, V1a, CAN, myeloperoxidase, HAD
Papers using ALI antibodies
Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection
Supplier
Namieśnik Jacek et al., In Analytical and Bioanalytical Chemistry, 2009
... studied artificial sweeteners were obtained from different sources: ACS-K from Nutrinova (Frankfurt am Main, Germany), ALI from Frapp’s Pharma (Hong Kong, China), ASP from Ajinomoto (Switzerland), CYC from Merck (Germany), NEO from CHEMOS ...
Papers on ALI
Mesenchymal Stem Cells Alleviate LPS-Induced Acute Lung Injury in Mice by MiR-142a-5p-Controlled Pulmonary Endothelial Cell Autophagy.
New
You et al., Taizhou, China. In Cell Physiol Biochem, Feb 2016
BACKGROUND/AIMS: Damages of pulmonary endothelial cells (PECs) represent a critical pathological process during acute lung injury (ALI), and precede pulmonary epithelial cell injury, and long-term lung dysfunction.
Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice.
New
Xu et al., Beijing, China. In Int J Mol Med, Feb 2016
UNASSIGNED: Acute lung injury (ALI) as a serious diseases with high mortality and is considered a threat to human health and life.
Replication of an Autonomous Human Parvovirus in Non-dividing Human Airway Epithelium Is Facilitated through the DNA Damage and Repair Pathways.
New
Qiu et al., Iowa City, United States. In Plos Pathog, Jan 2016
In vitro, HBoV1 infects well-differentiated/polarized primary human airway epithelium (HAE) cultured at an air-liquid interface (HAE-ALI).
The predictive value of soluble endothelial selectin plasma levels in children with acute lung injury.
New
Mourad et al., Ţanţā, Egypt. In J Crit Care, Jan 2016
UNASSIGNED: The study aimed to evaluate the value of soluble endothelial selectin (sE-selectin) plasma level measurement in predicting acute lung injury (ALI) outcome in children.
Molecular mechanisms in lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.
Review
New
Kou et al., Nanjing, China. In Int Immunopharmacol, Dec 2015
Pulmonary endothelial barrier dysfunction is a pivotal early step in the development of a variety of high mortality diseases, such as acute lung injury (ALI).
[Effect of Tanshinone II A on Cytokines of Rats with Severe Acute Pancreatitis Lung Injury].
New
Shen et al., In Zhongguo Zhong Xi Yi Jie He Za Zhi, Nov 2015
OBJECTIVE: To explore the effect of Tanshinone II A on severe acute pancreatitis (SAP) lung injury (ALI) rats and its possible mechanism.
[Recent advances in the study of Nrf2 and inflammatory respiratory diseases].
Review
New
Hou et al., In Yao Xue Xue Bao, Sep 2015
More and more studies demonstrated that Nrf2 was a novel signaling molecule in the modulation of inflammatory responses in these inflammatory respiratory diseases, such as asthma, acute lung injury (ALI) and COPD.
The role of C5a in acute lung injury induced by highly pathogenic viral infections.
Review
New
Shen et al., Beijing, China. In Emerg Microbes Infect, May 2015
Unregulated complement activation is likely to play a crucial role in the pathogenesis of acute lung injury (ALI) induced by highly pathogenic virus including influenza A viruses H5N1, H7N9, and severe acute respiratory syndrome (SARS) coronavirus.
Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release.
New
Impact
Arditi et al., Los Angeles, United States. In Immunity, May 2015
Acute lung injury (ALI) remains a serious health issue with little improvement in our understanding of the pathophysiology and therapeutic approaches.
2D DIGE Does Not Reveal all: A Scotopic Report Suggests Differential Expression of a Single "Calponin Family Member" Protein for Tetany of Sphincters!
Review
Chaudhury, Little Rock, United States. In Front Med (lausanne), 2014
Using 2D differential gel electrophoresis (DIGE) and mass spectrometry (MS), a recent report by Rattan and Ali (2015) compared proteome expression between tonically contracted sphincteric smooth muscles of the internal anal sphincter (IAS), in comparison to the adjacent rectum [rectal smooth muscles (RSM)] that contracts in a phasic fashion.
Spatial control of membrane receptor function using ligand nanocalipers.
Impact
Teixeira et al., Stockholm, Sweden. In Nat Methods, 2014
Using these 'nanocalipers' to present ephrin ligands, we showed that the nanoscale spacing of ephrin-A5 directs the levels of EphA2 receptor activation in human breast cancer cells.
Acute lung injury and the role of histones.
Review
Grailer et al., Ann Arbor, United States. In Transl Respir Med, 2013
We have studied experimental acute lung injury (ALI) in mice following airway deposition of bacterial lipopolysaccharide (LPS) or the recombinant mouse complement anaphylatoxin, C5a.
A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke.
GeneRIF
Carmichael et al., Los Angeles, United States. In Proc Natl Acad Sci U S A, 2012
Ephrin-A5 is induced in reactive astrocytes in periinfarct cortex and is an inhibitor of axonal sprouting and motor recovery in stroke.
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.
Impact
Tuder et al., Aurora, United States. In Nat Med, 2012
Sepsis, a systemic inflammatory response to infection, commonly progresses to acute lung injury (ALI), an inflammatory lung disease with high morbidity.
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury.
Impact
Bhattacharya et al., New York City, United States. In Nat Med, 2012
Bone marrow-derived stromal cells (BMSCs) protect against acute lung injury (ALI).
Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.
GeneRIF
Zeng et al., Johnson City, United States. In J Neural Transm, 2012
This study presented that EFNA5 showed strong associations with alcohol withdrawal symptoms.
Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster α-Esterase-7.
GeneRIF
Kühnlein et al., Graz, Austria. In Insect Biochem Mol Biol, 2012
alpha-Est7 gene is not essential for Drosophila development but serves important functions for insecticide tolerance, lipid metabolism and lifespan control.
Concentration-dependent requirement for local protein synthesis in motor neuron subtype-specific response to axon guidance cues.
GeneRIF
Wichterle et al., New York City, United States. In J Neurosci, 2012
In a growth cone collapse assay, mouse embryonic stem cell-derived spinal motor neurons respond to ephrin-A5, semaphorin(Sema)3f, and Sema3a in a concentration-dependent manner.
EphrinA5 suppresses colon cancer development by negatively regulating epidermal growth factor receptor stability.
GeneRIF
Chen et al., Taiwan. In Febs J, 2012
Data suggest that ephrinA5 mRNA/protein levels are reduced in colon adenocarcinoma compared to normal colon tissue; staging/grading indicates that ephrinA5 inhibits colon adenocarcinoma progression via c-Cbl-mediated EGFR ubiquitination/degradation.
Two-photon probes for intracellular free metal ions, acidic vesicles, and lipid rafts in live tissues.
Impact
Cho et al., Seoul, South Korea. In Acc Chem Res, 2009
The resulting probes-AMg1 (Mg(2+)), ACa1-ACa3 (Ca(2+)), AZn1 and AZn2 (Zn(2+)), AH1, AH2, and AL1 (acidic vesicles), and CL2 (membrane)-use 2-acetyl-6-aminonaphthalene as the fluorophore and receptors for the target ions or membrane.
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