Mesoamerican Nephropathy or Global Warming Nephropathy?
Aurora, United States. In Blood Purif, Feb 2016
Potential mechanisms include the development of hyperosmolarity with the activation of the aldose reductase-fructokinase pathway in the proximal tubule leading to local injury and inflammation, and the possibility that renal injury may be the consequence of repeated uricosuria and urate crystal formation as a consequence of both increased generation and urinary concentration, similar to a chronic tumor lysis syndrome.
Potential Bioactive Compounds from Seaweed for Diabetes Management.
Kuala Lumpur, Malaysia. In Mar Drugs, Aug 2015
In this review, we discussed the diversity of seaweed composition and bioactive compounds which are potentially useful in preventing or managing T2DM by targeting various pharmacologically relevant routes including inhibition of enzymes such as α-glucosidase, α-amylase, lipase, aldose reductase, protein tyrosine phosphatase 1B (PTP1B) and dipeptidyl-peptidase-4 (DPP-4).
Update on genetics and diabetic retinopathy.
Miami, United States. In Clin Ophthalmol, 2014
Multiple smaller studies have investigated genotype-phenotype correlations in genes encoding vascular endothelial growth factor, aldose reductase, the receptor for advanced glycation end products, and many others.