Genetic susceptibility factors for alcohol-induced chronic pancreatitis.
Greifswald, Germany. In Pancreatology, 31 Jul 2015
Smaller studies in ethnically defined populations have found that not only polymorphism in proteins involved in the metabolism of ethanol, such as Alcohol Dehydrogenase and Aldehyde Dehydrogenase, can confer a risk for developing chronic pancreatitis but also mutations that had previously been reported in association with idiopathic pancreatitis, such as SPINK1 mutations.
A molecular basis for heterosis.
In Science, 1969
Alcohol dehydrogenase allodimers composed of an unstable active subunit and a stable but inactive subunit are both active and stable.