Structure of AKR1C3 with 3-phenoxybenzoic acid bound.
Auckland, New Zealand. In Acta Crystallogr Sect F Struct Biol Cryst Commun, 2012
determined the X-ray crystal structure of AKR1C3 with the cofactor NADP+ and the drug-like inhibitor 3-phenoxybenzoic acid bound at a resolution of 1.68 A degrees in space group P212121
RGD peptides induce apoptosis by direct caspase-3 activation.
Birmingham, United Kingdom. In Nature, 1999
On the basis of the ability of RGD-DDX interactions to trigger integrin activation, we suggest that RGD peptides induce apoptosis by triggering conformational changes that promote pro-caspase-3 autoprocessing and activation.