gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Neurogenin 1

AKA, Ngn1, neurogenin1, NEUROG1
may play a role in neuronal differentiation [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, RUNX3, Insulin-Like Growth Factor II, MLH1, p16
Papers on AKA
Fragment quantum chemical approach to geometry optimization and vibrational spectrum calculation of proteins.
He et al., Shanghai, China. In Phys Chem Chem Phys, Feb 2016
The first and second derivatives of the EE-GMFCC energy are derived and employed in geometry optimization and vibrational frequency calculations for several test systems, including a polypeptide ((GLY)6), an α-helix (AKA), a β-sheet (Trpzip2) and ubiquitin (76 residues with 1231 atoms).
Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease.
Finazzi et al., Brescia, Italy. In Neurobiol Dis, Jan 2016
We characterized the CNS phenotype by studying the expression pattern of wnt1 and neurog1 neural markers and by use of the Tg(neurod:EGFP/sox10:dsRed) transgenic line.
Activation of AKT1/GSK-3β/β-Catenin-TRIM11/Survivin Pathway by Novel GSK-3β Inhibitor Promotes Neuron Cell Survival: Study in Differentiated SH-SY5Y Cells in OGD Model.
Ramanathan et al., Coimbatore, India. In Mol Neurobiol, Jan 2016
During differentiation, upregulation of the growth-associated protein 43 (GAP43), neurogenin1 (NGN1), neuronal differentiation 2 (NeuroD2), and tripartite motif containing 11 (TRIM11) genes were observed.
Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway.
Hsu et al., T'ai-chung-shih, Taiwan. In Mol Neurobiol, Jan 2016
In the zebrafish model, knockdown of diras1a and/or diras1b by morpholino antisense oligonucleotides not only reduced axon guidance but also caused the loss of trigeminal ganglion without affecting the precursor markers, such as ngn1 and neuroD.
Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ.
Chen et al., Nanjing, China. In Dis Model Mech, Jan 2016
In seipin-nKO mice, the hippocampal Wnt3 protein level was less than that in WT mice, and there was a reduction of neurogenin 1 (Neurog1) and neurogenic differentiation 1 (NeuroD1) mRNA, levels of which were corrected by rosi treatment.
Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B.
Zhou et al., United States. In Gene, Dec 2015
Also, mutations in CUL4B have been implicated in a subset of patients suffering from syndromic X-linked intellectual disability (AKA mental retardation).
Evaluation of CpG Island Methylator Phenotype as a Biomarker in Colorectal Cancer Treated With Adjuvant Oxaliplatin.
Grady et al., Seattle, United States. In Clin Colorectal Cancer, Dec 2015
CIMP status was determined using the DNA methylation status of CACNA1G, IGF2, NEUROG1, RUNX3, and SOCS1.
Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish.
Drapeau et al., Montréal, Canada. In Dev Neurobiol, Oct 2015
We used well-known transgenic lines in which expression of green fluorescent protein (GFP) is driven by promoters to hb9 and isl1 in motoneurons, alx/chx10 and evx1 interneurons, ngn1 in sensory neurons and olig2 in oligodendrocytes, as well as antibodies for neurons (HuC/D, NF and SV2) and glia (GFAP).
Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification.
Sun et al., Los Angeles, United States. In Elife, 2014
It has been postulated that a proneural factor, neurogenin 1 (Ngn1), simultaneously activates the neurogenic program and inhibits the alternative astrogliogenic program when specifying the neuronal fate.
Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature.
Vendraminelli et al., Verona, Italy. In Int J Surg Pathol, 2012
The promoter regions of subset of genes highly specific to characterize the CIMP status (NEUROG1, IGF2, RUNX3, SOCS1, including MLH1) were hypermethylated, suggesting the presence of CIMP+ and MSI high tumor.
Differential contribution of Neurog1 and Neurog2 on the formation of cranial ganglia along the anterior-posterior axis.
Gaufo et al., San Antonio, United States. In Dev Dyn, 2012
the formation of cranial ganglia along the anterior-posterior axis is dependent on the dynamic spatiotemporal activities of Neurog1 and/or Neurog2 in both neural crest and epibranchial placode.
Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.
Fritzsch et al., Iowa City, United States. In Plos One, 2011
Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.
Zebrafish Dmrta2 regulates neurogenesis in the telencephalon.
Kikuchi et al., Hiroshima, Japan. In Genes Cells, 2011
zebrafish Dmrta2 controls neurogenin1 expression by repressing her6 in the posterior-dorsal telencephalon
TACE cleaves neogenin to desensitize cortical neurons to the repulsive guidance molecule.
Yamashita et al., Suita, Japan. In Neurosci Res, 2011
Tumor necrosis factor-alpha converting enzyme (TACE) may play a role in modulating repulsive guidance molecule (RGM)-induced repulsive behavior of neurons by regulating neogenin expression on the cell surface.
Myt/NZF family transcription factors regulate neuronal differentiation of P19 cells.
Marunouchi et al., Japan. In Neurosci Lett, 2011
Neural zinc finger (NZF)-3 works downstream of Neurog1 and plays a crucial role together with Neurog1 in neuronal differentiation.
Human ESC-derived neural crest model reveals a key role for SOX2 in sensory neurogenesis.
Terskikh et al., Los Angeles, United States. In Cell Stem Cell, 2011
We found that SOX2 binds directly to NGN1 and MASH1 promoters and is required for their expression.
Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Ogino et al., Boston, United States. In Int J Cancer, 2011
We analyzed for LINE-1 hypomethylation and hypermethylation at 7 CIMP-specific CpG islands (CACNA1G, CRABP1, IGF2, MLH1, NEUROG1, RUNX3 and SOCS1); microsatellite instability (MSI); KRAS, BRAF and PIK3CA mutations; and expression of TP53 (p53), CTNNB1 (β-catenin), CDKN1A (p21), CDKN1B (p27), CCND1 (cyclin D1), FASN (fatty acid synthase) and PTGS2 (cyclooxygenase-2).
Conserved non-coding sequences and transcriptional regulation.
Rastegar et al., Karlsruhe, Germany. In Brain Res Bull, 2008
Here, we summarise work of the past few years on the regulatory modules of the sonic hedgehog and neurogenin1 genes.
Anti-citrullinated protein antibodies in rheumatoid arthritis: as good as it gets?
Lakos et al., Debrecen, Hungary. In Clin Rev Allergy Immunol, 2008
The first members of this autoantibody family were anti-perinuclear factor (APF) and anti-keratin antibodies (AKA).
Group-specific component: evidence for two subtypes of the Gc1 gene.
Viau et al., In Science, 1978
Eight hundred samples were analyzed, including three different populations: Caucasoid (a western Pyrenean valley), African (Pygmy Bi-Aka), and AMerindian (Quechua-Aymara, from Bolivia).
share on facebooktweetadd +1mail to friends