Familial Isolated Pituitary Adenoma
Madagascar. In Unknown Journal, 2012
Of these FIPA families, around 15-20% (3,4) have been identified to have mutations within the aryl hydrocarbon receptor interacting protein (AIP) gene, a tumour suppressor gene located at 11q13.
WWP2 is an E3 ubiquitin ligase for PTEN.
Hyderābād, India. In Nat Cell Biol, 2011
In this study, by using a tandem affinity-purification approach, we have identified WWP2 (also known as atrophin-1-interacting protein 2, AIP-2) as a PTEN-interacting protein.