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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Angiogenic factor with G patch and FHA domains 1

AGGF1, VG5Q, angiogenic factor with G-patch and FHA domains 1, angiogenic factor VG5Q
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010] (from NCBI)
Papers on AGGF1
Sphingolipid modulation of angiogenic factor expression in neuroblastoma.
GeneRIF
Ferrer et al., Farmington, United States. In Cancer Prev Res (phila), 2011
Sphingolipid modulation of angiogenic factor expression in neuroblastoma
Novel roles of GATA1 in regulation of angiogenic factor AGGF1 and endothelial cell function.
GeneRIF
Wang et al., Cleveland, United States. In J Biol Chem, 2009
Knockdown of GATA1 expression by siRNA reduced expression of AGGF1, and resulted in endothelial cell apoptosis and inhibition of vessel formation.
Identification of association of common AGGF1 variants with susceptibility for Klippel-Trenaunay syndrome using the structure association program.
GeneRIF
Wang et al., Cleveland, United States. In Ann Hum Genet, 2008
identified two tagSNPs, rs13155212 and rs7704267 that capture information for all common variants in AGGF1 as a candidate susceptibility gene for Klippel-Trenaunay syndrome
Klippel-Trenaunay syndrome: a multisystem disorder possibly resulting from a pathogenic gene for vascular and tissue overgrowth.
GeneRIF
Janniger et al., Newark, United States. In Int J Dermatol, 2006
This review describes the somatic mutation for angiogenic factor VG5Q, which may be the cause of the multisystem disorder Klippel-Trenaunay syndrome.
Is the E133K allele of VG5Q associated with Klippel-Trenaunay and other overgrowth syndromes?
GeneRIF
Harper et al., In J Med Genet, 2006
VG5Q, E133K is a mutation that causes Klippel-Trenaunay and other overgrowth syndromes.
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