Considerations regarding current diagnosis and prognosis of hepatocellular carcinoma.
Craiova, Romania. In J Med Life, 30 Apr 2015
Abbreviations : AASLD = American Association for the Study of Liver Diseases, AFP = Alpha-fetoprotein, AFP-L3 = Alpha-fetoprotein isoform 3, CEUS = Contrast-enhanced ultrasonography, DCP = Des-gamma-carboxy-prothrombin, DW-MRI = Diffusion weighted magnetic resonance imaging, FNA = Fine neddle aspiration, Gd-EOB-DTPA = Gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid, GGT-II = Gamma-glutamyl transpeptidase II, GP73 = Golgi protein 73, HCC = Hepatocellular carcinoma, HCCR-1 = Human cervical cancer proto-oncogene 1, IL-18 = Interleukin 18, MDCT = Multi-detector computed tomography, PET-CT = Positron emission tomography - computed tomography, SUV = Standardized Uptake Value.
Serological prenatal screening and diagnosis for Down syndrome.
In Clin Exp Obstet Gynecol, 2013
MATERIALS AND METHODS: This study included 3,665 cases of 14-20-week pregnant women that underwent prenatal screening using double serum alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (beta-hCG) and ultrasound screening; 512 cases of 9-12-week pregnant women underwent triple serological detection of serum beta-hCG, pregnancy-associated plasma protein A (PAPP-A), and nuchal translucency (NT) for early screening.
Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study.
Shanghai, China. In Lancet Oncol, 2012
Furthermore, DKK1 maintained diagnostic accuracy for patients with HCC who were α-fetoprotein (AFP) negative (0·841 [0·801-0·882], 70·4%, and 90·0% in the test cohort; 0·869 [0·815-0·923], 66·7%, and 87·2% in the validation cohort), including for patients with early-stage HCC (0·870 [0·829-0·911], 73·1%, and 90·0% in the test cohort; 0·893 [0·804-0·983], 72·2%, and 87·2% in the validation cohort), compared with all controls.