337 promoter-dependent silencing of reprogramming transcription factors in mouse induced pluripotent stem cells produced with sleeping beauty transposon vectors.
Neustadt, Germany. In Reprod Fertil Dev, 31 Dec 2014
Moreover, these cells also showed ability to differentiate in vitro into cells from the 3 germ layers (contracting cardiac myocytes, neurons, epithelia) expressing differentiation markers Afp, Sox17, Gata4, Gata6, cardiac troponin, nestin, and PGP 9.5.
341 feline embryonic stem-like cells derived from in vitro-produced blastocysts retain in vitro differentiation potential.
Bangkok, Thailand. In Reprod Fertil Dev, 31 Dec 2014
In vitro differentiation into embryoid bodies (EB) was induced by the hanging drop technique, and EB samples (n=5 for each time point) were tested for the expression of TTR, AFP, T (Bracyury), NKX2.5, MAP-2, and NESTIN genes at 0, 7, and 14 days of culture.
Alpha-fetoprotein: a renaissance.
Moscow, Russia. In Tumour Biol, Aug 2013
Alpha-fetoprotein (AFP) is a major mammalian embryo-specific and tumor-associated protein that is also present in small quantities in adults at normal conditions.
Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study.
Shanghai, China. In Lancet Oncol, 2012
Furthermore, DKK1 maintained diagnostic accuracy for patients with HCC who were α-fetoprotein (AFP) negative (0·841 [0·801-0·882], 70·4%, and 90·0% in the test cohort; 0·869 [0·815-0·923], 66·7%, and 87·2% in the validation cohort), including for patients with early-stage HCC (0·870 [0·829-0·911], 73·1%, and 90·0% in the test cohort; 0·893 [0·804-0·983], 72·2%, and 87·2% in the validation cohort), compared with all controls.