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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

AE binding protein 2

Top mentioned proteins: Polycomb, Histone, Jumonji, SUZ12, CHIP
Papers on AEBP2
AEBP2 as a transcriptional activator and its role in cell migration.
Kim et al., Baton Rouge, United States. In Genomics, Feb 2015
Aebp2 encodes an evolutionarily conserved zinc finger protein that has not been well studied so far, yet recent studies indicated that this gene is closely associated with the Polycomb Repressive Complex 2 (PRC2).
Retrotransposon-derived promoter of Mammalian Aebp2.
Kim et al., Baton Rouge, United States. In Plos One, 2014
The current study analyzed the evolutionary origin and DNA methylation pattern of one of the promoters of Aebp2.
Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression.
Müller et al., Martinsried, Germany. In Nat Struct Mol Biol, 2014
We show that monoubiquitination of histone H2A by PRC1-type complexes to form H2Aub creates a binding site for Jarid2-Aebp2-containing PRC2 and promotes H3K27 trimethylation on H2Aub nucleosomes.
Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification.
Kuroda et al., Boston, United States. In Proc Natl Acad Sci U S A, 2014
We identify and validate two strong interactors, C10orf12 and C17orf96, which display enrichment with EZH2-BioTAP at levels similar to canonical PRC2 components (SUZ12, EED, MTF2, JARID2, PHF1, and AEBP2).
Profiling of embryonic stem cell differentiation.
Kume et al., Kumamoto, Japan. In Rev Diabet Stud, 2013
Akr1c19, Aebp2, Pbxip1, and Creb3l1 were all novel, and none has been described as being expressed, either in the DE, or in the pancreas.
Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies.
Kralovics et al., Vienna, Austria. In Am J Hematol, 2012
Subsequently, analysis of deletion profiles of other PRC2 members revealed frequent losses of genes such as EZH2, AEBP2, and SUZ12; however, the deletions targeting these genes were large.
Recruitment and biological consequences of histone modification of H3K27me3 and H3K9me3.
Kim et al., Baton Rouge, United States. In Ilar J, 2011
Recent studies have shown that the targeting of these histone-modifying complexes within mammalian genomes may be mediated through several DNA-binding proteins, including AEBP2, JARID2, and YY1.
Molecular architecture of human polycomb repressive complex 2.
Nogales et al., Berkeley, United States. In Elife, 2011
Polycomb Repressive Complex 2 (PRC2) is essential for gene silencing, establishing transcriptional repression of specific genes by tri-methylating Lysine 27 of histone H3, a process mediated by cofactors such as AEBP2.
An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.
Kume et al., Kumamoto, Japan. In Bmc Dev Biol, 2010
Akr1c19, Aebp2, Pbxip1 and Creb3l1, were novel and have not been described as being expressed either in DE or the pancreas.
Aebp2 as an epigenetic regulator for neural crest cells.
Kim et al., Baton Rouge, United States. In Plos One, 2010
Aebp2 is a potential targeting protein for the mammalian Polycomb Repression Complex 2 (PRC2).
Characterization of the tandem CWCH2 sequence motif: a hallmark of inter-zinc finger interactions.
Aruga et al., Wako, Japan. In Bmc Evol Biol, 2009
We categorized genes into 11 classes including Zic/Gli/Glis, Arid2/Rsc9, PacC, Mizf, Aebp2, Zap1/ZafA, Fungl, Zfp106, Twincl, Clr1, and Fungl-4ZF, based on sequence similarity, domain organization, and functional similarities.
AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.
Kim et al., Baton Rouge, United States. In Nucleic Acids Res, 2009
A large fraction of AEBP2's target loci also map closely to the known target loci of the Polycomb Repression Complex PRC2.
Laser microdissection and microarray analysis of the hippocampus of Ras-GRF1 knockout mice reveals gene expression changes affecting signal transduction pathways related to memory and learning.
Santos et al., Salamanca, Spain. In Neuroscience, 2007
Indeed, potential links to neurodegenerative diseases such as Alzheimer disease (AD) or Creutzfeldt-Jacobs disease (CJD), have been reported for a number of differentially expressed genes identified in this study (Ptma, Aebp2, Clasp2, Hebp1, 14-3-3gamma/zeta, Csnk1delta, etc.).
SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex.
Zhang et al., Chapel Hill, United States. In Mol Cell, 2004
We found that the HMTase activity requires a minimum of three components-EZH2, EED, and SUZ12-while AEBP2 is required for optimal enzymatic activity.
The jing Zn-finger transcription factor is a mediator of cellular differentiation in the Drosophila CNS midline and trachea.
Sonnenfeld et al., Ottawa, Canada. In Development, 2002
Given the similarities between JING and the vertebrate CCAAT-binding protein AEBP2, we propose that jing regulates transcriptional mechanisms in Drosophila embryos and promotes cellular differentiation in ectodermal derivatives.
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