adenosine A2B receptor
Anesthetic cardioprotection: the role of adenosine.
Aurora, United States. In Curr Pharm Des, 2013
As such, the adenosine A2b receptor was shown to be the only one of the adenosine receptors whose cardiac expression is induced by ischemia in both mice and humans and whose function is implicated in ischemic pre- or post-conditioning.
A role for period 2 in cardioprotection.
In Cell Metab, 2012
Eckle et al. (2012) now show that signaling through adenosine receptor 2b (Adora2b) stabilizes a circadian rhythm protein, period 2 (Per2), resulting in the stabilization of hypoxia-inducible factor-1α (HIF-1α), upregulation of glycolysis, and cardioprotection from ischemia.
The adenosine a2b receptor: its role in inflammation.
Cardiff, United Kingdom. In Endocr Metab Immune Disord Drug Targets, 2008
Investigations into the role of the adenosine A2b receptor have been enigmatic due to the lack of good selective high affinity agonists and antagonists.