gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Acetylcholinesterase

acetylcholinesterase, AChE
Top mentioned proteins: CAN, Cholinesterase, ACID, HAD, V1a
Papers using acetylcholinesterase antibodies
Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia
Supplier
Soreq Hermona et al., In Frontiers in Molecular Neuroscience, 2009
... ) report for several of the latter technologies used to explore the miR-132 target AChE, and (Hansen et al., 2010) for the “classical” 3′-UTR and transgenic approaches, in exploring p250GAP ...
The PyMOL Molecular Graphics System
Supplier
Darvesh Sultan et al., In Biochemistry, 2001
... ), and purified recombinant human AChE (∼1500, units as determined by the supplier) were purchased from Sigma Aldrich (St ...
Papers on acetylcholinesterase
AChE inhibition-based multi-target-directed ligands, a novel pharmacological approach for the symptomatic and disease-modifying therapy of Alzheimer's disease.
New
Chen et al., Shanghai, China. In Curr Neuropharmacol, Feb 2016
To date acetylcholinesterase inhibitors (AChEIs) have become the most prescribed drugs for the symptomatic treatment of mild to moderate AD.
Emerging treatments in neurogastroenterology: Acotiamade, a novel treatment option for functional dyspepsia.
Review
New
Suzuki et al., Tokyo, Japan. In Neurogastroenterol Motil, Feb 2016
The agent inhibits acetylcholinesterase in vitro and enhances muscle motility ex vivo.
Design and discovery of Novel Thiazole acetamide derivatives as anticholinesterase agent for possible role in the management of Alzheimer's.
New
Liu et al., Linyi, China. In Bioorg Med Chem Lett, Feb 2016
These compounds were evaluated for in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities for possible benefit in Alzheimers disease (AD).
Acetylcholinesterase Inhibitors for Delirium in Older Adults.
Review
New
Ghori et al., Hartford, United States. In Am J Alzheimers Dis Other Demen, Jan 2016
OBJECTIVES: The aim of this systematic review is to identify published randomized controlled trials (RCTs) that evaluated the use of acetylcholinesterase inhibitors for delirium in older adults (≥60 years).
Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals.
New
Bond et al., In J Vis Exp, Dec 2015
Exosomes were identified on the basis of exosome markers acetylcholinesterase (AChE), and the CD9, CD63, and CD45 antigens.
Environmental Fate and Toxicology of Dimethoate.
Review
New
Zhang et al., Sacramento, United States. In Rev Environ Contam Toxicol, Dec 2015
It is known to inhibit AChE activity like other organophosphates, resulting in nerve damage which may lead to death.
Repeated administration of an acetylcholinesterase inhibitor attenuates nicotine taking in rats and smoking behavior in human smokers.
New
Schmidt et al., Philadelphia, United States. In Transl Psychiatry, Dec 2015
Our previous studies demonstrated that acute administration of an acetylcholinesterase inhibitor (AChEI) attenuates nicotine taking and seeking in rats and suggest that AChEIs could be repurposed for smoking cessation.
Organophosphate pesticide exposure and neurodegeneration.
Review
New
Herrero Hernández et al., Almería, Spain. In Cortex, Nov 2015
Apart from the principle action of OPs which involves inhibition of the acetylcholinesterase (AChE) enzyme, several molecular targets, such as hormones; neurotransmitters; neurotrophic factors; enzymes related to the metabolism of beta amyloid protein as well as inflammatory changes have been identified for OP compounds.
Role of α7 nicotinic receptor in the immune system and intracellular signaling pathways.
Review
Lewicki et al., Warsaw, Poland. In Cent Eur J Immunol, 2014
The non-neuronal acetylcholine is accompanied by the expression of acetylcholinesterase and nicotinic/muscarinic acetylcholine receptors.
Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial.
Impact
Guarino et al., Minneapolis, United States. In Jama, 2014
OBJECTIVE: To determine if vitamin E (alpha tocopherol), memantine, or both slow progression of mild to moderate AD in patients taking an acetylcholinesterase inhibitor.
Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial.
Impact
Miller et al., San Francisco, United States. In Lancet Neurol, 2013
Use of acetylcholinesterase inhibitors was prohibited.
Automated design of ligands to polypharmacological profiles.
Impact
Hopkins et al., Dundee, United Kingdom. In Nature, 2013
The method is demonstrated by the evolution of an approved acetylcholinesterase inhibitor drug into brain-penetrable ligands with either specific polypharmacology or exquisite selectivity profiles for G-protein-coupled receptors.
Valuing the Endangered Species Antirrhinum lopesianum: Neuroprotective Activities and Strategies for in vitro Plant Propagation.
Santos et al., Lisbon, Portugal. In Antioxidants (basel), 2012
Plant phytochemicals are described as possessing considerable neuroprotective properties, due to radical scavenging capacity and acetylcholinesterase inhibitory activity, important bioactivities in neurodegeneration.
Endosulfan exposure inhibits brain AChE activity and impairs swimming performance in adult zebrafish (Danio rerio).
GeneRIF
Bogo et al., Porto Alegre, Brazil. In Neurotoxicology, 2012
Endosulfan exposure inhibits brain Ache activity and significantly impairs animals' exploratory performance, and potentially compromises their ecological and interspecific interaction.
Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.
Impact
Renard et al., Mont-Saint-Aignan, France. In Acc Chem Res, 2012
The acute toxicity of OPNAs results from the irreversible inhibition of acetylcholinesterase (AChE, EC 3.1.1.7)
Microcystin-LR acute exposure increases AChE activity via transcriptional ache activation in zebrafish (Danio rerio) brain.
GeneRIF
Bogo et al., Porto Alegre, Brazil. In Comp Biochem Physiol C Toxicol Pharmacol, 2012
Findings provide evidence that brain acetylcholinesterase (AChE) is a potential target for microcystins (MCs).
Chemically engineered extracts: source of bioactive compounds.
Review
Impact
Furlan et al., Rosario, Argentina. In Acc Chem Res, 2011
We isolated a semisynthetic β-glucosidase inhibitor from a CEE prepared by reaction with benzenesulfonyl chloride, an antifungal pyrazole from a CEE prepared by reaction with hydrazine, and an acetylcholinesterase inhibitor from a CEE prepared through bromination.
Expression of acetylcholinesterase (AChE) and aryl acylamidase (AAA) during early zebrafish embryogenesis.
GeneRIF
Layer et al., Darmstadt, Germany. In Chem Biol Interact, 2006
aryl acylamidase associated with acetylcholinesterase was higher than the esterase activity on zebrafishembryo
Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability.
GeneRIF
Granato et al., Philadelphia, United States. In Dev Biol, 2004
Results demonstrate that AChE is dispensable for its proposed non-classical roles in muscle fiber formation and sensory neuron development, but is crucial for regulating the stability of neuromuscular synapses.
share on facebooktweetadd +1mail to friends