Regulation of isoprenoid pheromone biosynthesis in bumblebee males.
Praha, Czech Republic. In Chembiochem, Jan 2016
RNA-seq and qRT-PCR analyses indicated that acetoacetyl-CoA thiolase (AACT), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR), and farnesyl diphosphate synthase (FPPS) transcripts are abundant in the B. terrestris labial gland.
Inborn errors of ketone body utilization.
Gifu, Japan. In Pediatr Int, Feb 2015
Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency and mitochondrial acetoacetyl-CoA thiolase (beta-ketothiolase or T2) deficiency are classified as autosomal recessive disorders of ketone body utilization characterized by intermittent ketoacidosis.
First report of 3-oxothiolase deficiency in iran.
Sārī, Iran. In Int J Endocrinol Metab, 2014
INTRODUCTION: Mitochondrial acetoacetyl-CoA thiolase (3-oxothiolase) deficiency is a rare metabolic disorder involving ketone body metabolism characterized by acute attacks of vomiting, acidosis, ketosis, and lethargy along with some laboratory criteria including excessive excretion of 2-methyl-3-hydroxybutyric acid in urine.
Enzymes of the mevalonate pathway of isoprenoid biosynthesis.
Kansas City, United States. In Arch Biochem Biophys, 2011
The biosynthetic acetoacetyl-CoA thiolase and HMG-CoA synthase reactions rely on key amino acids that are different but are situated in active sites that are similar throughout the family of initial condensation enzymes.
Inborn errors of isoleucine degradation: a review.
Jerusalem, Israel. In Mol Genet Metab, 2006
Deficiency of beta-ketothiolase (beta-KT, also known as T2, mitochondrial acetoacetyl-CoA thiolase and acetyl-CoA acetyltransferase 1) is a well-described disorder which presents with acute episodic ketoacidosis.