Multifunctional Abl kinases in health and disease.
Durham, United States. In J Cell Sci, Feb 2016
The Abl family kinases Abl1 and Abl2 regulate diverse cellular processes during development and normal homeostasis, and their functions are subverted during inflammation, cancer and other pathologies.
Novel therapies in small cell lung cancer.
Indianapolis, United States. In Transl Lung Cancer Res, Oct 2015
Several of them including EGFR TKIs, BCR-ABL TKIs, mTOR inhibitors, and VEGF inhibitors have been unsuccessful in showing a survival advantage in this disease.
Hsp90 Inhibitors for the Treatment of Chronic Myeloid Leukemia.
More papers using
Pondicherry, India. In Leuk Res Treatment, 2014
Chronic myeloid leukemia (CML) is a hematological malignancy that arises due to reciprocal translocation of 3' sequences from c-Abelson (ABL) protooncogene of chromosome 9 with 5' sequence of truncated break point cluster region (BCR) on chromosome 22.