Papers on
A1B
Structure and function of Gab2 and its role in cancer (Review).Luo et al., Zunyi, China. In Mol Med Report, Sep 2015
The docking proteins of the Grb-associated binder (Gab) family transduce cellular signals between receptors and intracellular downstream effectors, and provide a platform for protein‑protein interactions.
Essential roles of Gab1 tyrosine phosphorylation in growth factor-mediated signaling and angiogenesis.Jin et al., Rochester, United States. In Int J Cardiol, Mar 2015
Recent studies have revealed that Grb2-associated-binders (Gab) family members (including Gab1, Gab2, and Gab3), when phosphorylated on tyrosine residues, provide binding sites for multiple effector proteins, such as Src homology-2 (SH2)-containing protein tyrosine phosphatase 2 (SHP2) and phosphatidylinositol 3-kinase (PI3K) regulatory subunit p85, thereby playing important roles in transducing RTKs-mediated signals into pathways with diversified biological functions.
The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico.Yamamura et al., Ponce, Puerto Rico. In Int J Environ Res Public Health, 2014
Though there were fewer cases, the following subtypes were also found (in the given proportions): A1B (0.3%), BF1 (0.2%), subtype A (01-AE) (0.1%), subtype A (A2) (0.1%), subtype F (12BF) (0.1%), CRF-39 BF-like (0.1%), and others (0.1%).
The velocity of climate change.Ackerly et al., Stanford, United States. In Nature, 2010
This index represents the instantaneous local velocity along Earth's surface needed to maintain constant temperatures, and has a global mean of 0.42 km yr(-1) (A1B emission scenario).
Essential role for Gab2 in the allergic response.Neel et al., Boston, United States. In Nature, 2001
Dos/Gab family scaffolding adapters (Dos, Gab1, Gab2) bind several signal relay molecules, including the protein-tyrosine phosphatase Shp-2 and phosphatidylinositol-3-OH kinase (PI(3)K); they are also implicated in growth factor, cytokine and antigen receptor signal transduction.
Cerebral thrombosis, cerebral haemorrhage, and ABO blood-groups.Bicescu et al., In Lancet, 1976
A statistically significant difference did emerge when the A+AB excess in thrombosis was contrasted with the O+B excess in haemorrhage, suggesting that this difference might be accounted for the major A subgroup (A1) and, consequently, A1B.