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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


a type I transmembrane protein, a type 1 transmembrane protein
Top mentioned proteins: ACID, CAN, CD45, V1a, APP
Papers on a type I transmembrane protein
Crim1 regulates integrin signaling in murine lens development.
Maas et al., Boston, United States. In Development, Feb 2016
Cysteine-rich motor neuron 1 (Crim1), a type I transmembrane protein, is strongly expressed in the developing lens and its mutation causes ocular disease in both mice and humans.
Overexpression of Swedish mutant APP in aged astrocytes attenuates excitatory synaptic transmission.
Iwasaki et al., Fukuoka, Japan. In Physiol Rep, Jan 2016
Amyloid precursor protein (APP), a type I transmembrane protein, has different aspects, namely, performs essential physiological functions and produces β-amyloid peptide (Aβ).
Cathepsin D and its newly identified transport receptor Sez6l2 can modulate neurite outgrowth.
Jadot et al., Namur, Belgium. In J Cell Sci, Jan 2016
We demonstrate that cathepsin D binds to mouse Sez6l2, a type 1 transmembrane protein predominantly expressed in brain.
Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry.
Spiegelman et al., Boston, United States. In Cell Metab, Nov 2015
We have shown previously that FNDC5, a type I transmembrane protein, and its circulating form, irisin, convey some of these benefits in mice.
By inhibiting Ras/Raf/ERK and MMP-9, knockdown of EpCAM inhibits breast cancer cell growth and metastasis.
Yang et al., Dalian, China. In Oncotarget, Oct 2015
Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane protein that is expressed in the majority of normal epithelial tissues and is overexpressed in most epithelial cancers including breast cancer, where it plays an important role in cancer progression.
Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding.
Becker-Pauly et al., Kiel, Germany. In Biochem J, Sep 2015
Meprin β is a type 1 transmembrane protein, but can be released from the cell surface by ectodomain shedding.
The Role of SORL1 in Alzheimer's Disease.
Tan et al., Qingdao, China. In Mol Neurobiol, Jun 2015
As a type I transmembrane protein, SORL1 is composed of several distinct domains and belongs to both the low-density lipoprotein receptor (LDLR) family and the vacuolar protein sorting 10 (VPS10) domain receptor family.
MUC1-mediated motility in breast cancer: a review highlighting the role of the MUC1/ICAM-1/Src signaling triad.
Hugh et al., Edmonton, Canada. In Clin Exp Metastasis, Apr 2015
MUC1 is a type 1 transmembrane protein whose cytoplasmic tail acts as a scaffold for several signaling pathways including the non-receptor kinase Src, a signaling molecule involved in cell differentiation, proliferation, adhesion and motility.
MUC1: a novel metabolic master regulator.
Singh et al., Omaha, United States. In Biochim Biophys Acta, 2014
MUC1, a type I transmembrane protein, is significantly overexpressed and aberrantly glycosylated in tumors of epithelial origin.
Beyond dsRNA: Toll-like receptor 3 signalling in RNA-induced immune responses.
Matsumoto et al., Sapporo, Japan. In Biochem J, 2014
Endosomal TLR3 (Toll-like receptor 3), a type I transmembrane protein, senses RNAs derived from cells with viral infection or sterile tissue damage, leading to the induction of type I interferon and cytokine production, as well as dendritic cell maturation.
CD33 in Alzheimer's disease.
Tan et al., Nanjing, China. In Mol Neurobiol, 2014
As a type I transmembrane protein, CD33 belongs to the sialic acid-binding immunoglobulin-like lectins, mediating the cell-cell interaction and inhibiting normal functions of immune cells.
Expression of amnionless in mouse testes and Leydig cells.
Gye et al., Seoul, South Korea. In Andrologia, 2012
AMN may participate in meiosis in early spermatocytes and in functional differentiation of adult Leydig cells through the mediation of vitamin B(12) transport in the mouse testes
Identification of Tim4 as a phosphatidylserine receptor.
Nagata et al., Kyoto, Japan. In Nature, 2007
The antigen recognized by the antibody was identified by expression cloning as a type I transmembrane protein called Tim4 (T-cell immunoglobulin- and mucin-domain-containing molecule; also known as Timd4).
Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules.
Lacy et al., New York City, United States. In Development, 2004
Amn is an essential component of the Cubn receptor complex
GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells.
Soares et al., Stanford, United States. In Immunity, 2003
GRAIL is a type I transmembrane protein that localizes to the endocytic pathway and bears homology to RING zinc-finger proteins.
Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia.
de la Chapelle et al., Columbus, United States. In Nat Genet, 2003
The amnionless gene, Amn, on mouse chromosome 12 encodes a type I transmembrane protein that is expressed in the extraembryonic visceral layer during gastrulation.
The molecular characterization of the fetal stem cell marker AA4.
Lemischka et al., Princeton, United States. In Immunity, 1999
This molecule is a type I transmembrane protein whose overall structure suggests a role in cell adhesion.
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