Organelle-specific Hsp90 inhibitors.
Taegu, South Korea. In Arch Pharm Res, Sep 2015
The Hsp90 family in mammalian cells is composed of four major homologs: Hsp90α, Hsp90β, 94-kDa glucose-regulated protein (Grp94), and TNF receptor-associated protein 1 (Trap1).
Limb-girdle muscular dystrophy 2A.
Barcelona, Spain. In Handb Clin Neurol, 2010
This gene encodes for a 94-kDa nonlysosomal calcium-dependent cysteine protease and its function in skeletal muscle is not fully understood.