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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

General transcription factor II H, polypeptide 1

62-kDa
Top mentioned proteins: ACID, CAN, fibrillin-1, HAD, Phosphogluconate Dehydrogenase
Papers on 62-kDa
The clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brain.
New
Greene et al., Bethesda, United States. In J Cell Sci, Nov 2015
Knocking out GAK in fibroblasts caused inhibition of clathrin-dependent trafficking, which was rescued by expressing a 62-kDa fragment of GAK, comprising just the clathrin-binding and J-domains.
Hypothesis of demodicidosis rosacea flushing etiopathogenesis.
New
Orduz et al., Medellín, Colombia. In Med Hypotheses, Apr 2015
The antibodies against the GroEl chaperonin protein, a 62-kDa heat shock protein were found in the Bacillus oleronius isolated from Demodex mites, in rosacea patients.
Hepatoprotective effects of melatonin against pronecrotic cellular events in streptozotocin-induced diabetic rats.
Martinović et al., Belgrade, Serbia. In J Physiol Biochem, 2014
This was accompanied by improved necrotic markers of cellular damage: a significant reduction in cleavage of the DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP-1) into necrotic 55- and 62-kDa fragments, and inhibition of nucleus-to-cytoplasm translocation and accumulation in the serum of the high-mobility group box 1 (HMGB1) protein.
Identification of 62-kDa protein as an immunogenic antigen of Vibrio vulnificus for humans.
Sakagucmhi et al., Saga, Japan. In Fukuoka Igaku Zasshi, 2013
Although we could not demonstrate differences in antibody response between the groups, all sera showed a strong antibody response to a 62-kDa protein that was common to all strains examined.
Rat sperm immobilisation effects of a protein from Ricinus communis (Linn.): an in vitro comparative study with nonoxynol-9.
Indira et al., India. In Andrologia, 2012
Previous study conducted in our department showed that 50% ethanolic extract of the root of Ricinus communis possess reversible antifertility effect and a 62-kDa protein (Rp) from this extract is responsible for the antifertility effects.
Protein C.
Karlaftis et al., Buenos Aires, Argentina. In Methods Mol Biol, 2012
Protein C (PC) is a 62-kDa vitamin K-dependent plasma zymogen which, after activation to serine protease, plays an important role in the physiologic regulation of blood coagulation.
Positive correlation between serum immunoreactivity to Demodex-associated Bacillus proteins and erythematotelangiectatic rosacea.
Kavanagh et al., Ireland. In Br J Dermatol, 2012
The 62-kDa protein was characterized by LC-MS and showed homology to groEL chaperonin, which provokes a strong immune response in mammals.
Immunohistochemical localization of aggresomal proteins in glial cytoplasmic inclusions in multiple system atrophy.
Shimada et al., Kasugai, Japan. In Neuropathol Appl Neurobiol, 2012
Double immunofluorescence staining and quantitative analysis demonstrated that the majority of GCIs contained these proteins, as well as other aggresome-related proteins, such as Hsp70, Hsp90 and 62-kDa protein/sequestosome 1 (p62/SQSTM1).
Deletion of UL21 causes a delay in the early stages of the herpes simplex virus 1 replication cycle.
Duffy et al., Tuscaloosa, United States. In J Virol, 2012
The herpes simplex virus 1 (HSV-1) U(L)21 gene encodes a 62-kDa tegument protein with homologs in the alpha-, beta-, and gammaherpesvirus subfamilies.
Molecular cloning and characterization of a matrix metalloproteinase, from Caenorhabditis elegans: employed to identify homologous protein from Angiostrongylus cantonensis.
Wu et al., Guangzhou, China. In Parasitol Res, 2012
In the present study, we have cloned a gene named CEMMP62 from Caenorhabditis elegans, the putative 62-kDa protein that contained 579 residues with MMP-conserved catalytic domain known as ZnMc_MMP and showed high identities with MMPs from other nematodes, and demonstrated that the recombinant CEMMP62 (rCEMMP62) expressed and purified from Escherichia coli could have weak proteolytic activity on swine gelatin; Western blot analysis revealed that sera from BALB/c mice immunized by recombinant protein could recognize excretory-secretary antigens from Angiostrongylus cantonensis third-stage larvae (L3).
Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction.
Playford et al., Bethesda, United States. In J Biol Chem, 2011
Sorting nexin 27 (SNX27) is a 62-kDa protein localized to early endosomes and known to regulate the intracellular trafficking of ion channels and receptors.
Autophagy and p62 in cardiac proteinopathy.
GeneRIF
Wang et al., United States. In Circ Res, 2011
p62 is up-regulated in mouse proteinopathic hearts and promotes aggresome formation and autophagy activation and protects cardiomyocytes against proteotoxic stress
Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation.
GeneRIF
Moscat et al., Cincinnati, United States. In Mol Cell Biol, 2011
cdk1 phosphorylates p62 in vitro and in vivo at T269 and S272, which is necessary for the maintenance of appropriate cyclin B1 levels and the levels of cdk1 activity necessary to allow cells to properly enter and exit mitosis.
A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis.
GeneRIF
Moscat et al., Cincinnati, United States. In Embo Rep, 2010
p62 is a crucial regulator of ERK1 in metabolism
Role of protein kinase Czeta and its adaptor protein p62 in voltage-gated potassium channel modulation in pulmonary arteries.
GeneRIF
Perez-Vizcaino et al., Madrid, Spain. In Mol Pharmacol, 2007
These data demonstrate that PKCzeta and its adaptor protein p62 play a key role in the modulation of K(V) channel function in pulmonary arteries.
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.
Impact
GeneRIF
Moscat et al., Madrid, Spain. In Cell Metab, 2006
p62 normally antagonizes basal ERK activity and adipocyte differentiation and that its loss leads to the hyperactivation of ERK that favors adipogenesis and obesity.
MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation.
Review
Breit et al., Sydney, Australia. In J Leukoc Biol, 1999
MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulfide-linked dimeric protein.
Immunodiagnosis of nocardiosis.
Review
Stynen et al., Paris, France. In Gene, 1992
Each of the serum samples from immunosuppressed or immunocompetent patients infected with N. asteroides reacted with the 54-kDa band, and two reacted with the 31- and 62-kDa bands.
Molecular differentiation in pea powdery-mildew haustoria : Identification of a 62-kDa N-linked glycoprotein unique to the haustorial plasma membrane.
Green et al., Birmingham, United Kingdom. In Planta, 1991
Western blotting and antigen-modification techniques have shown that UB8 recognises a protein epitope of a 62-kDa antigen.
Localization of a protein, immunologically similar to a sucrose-binding protein from developing soybean cotyledons, on the plasma membrane of sieve-tube members of spinach leaves.
Hitz et al., Beltsville, United States. In Planta, 1989
Immunocytochemical studies using antibodies raised against a 62-kDa membrane protein isolated from developing soybean (Glycine max (L.) Merr.) cotyledons were performed on leaf tissue of spinach (Spinacia oleracea L.).
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