Hypoxia-inducible factor as an angiogenic master switch.
New Haven, United States. In Front Pediatr, 2014
Eukaryotic initiation factor 3 subunit e (eIF3e)/INT6 interacts specifically with HIF-2α and induces the proteasome inhibitor-sensitive degradation of HIF-2α, independent of hypoxia and von Hippel-Lindau protein.
[Frequency of diseases caused by group A streptococci among invasive infections of soft tissues and characteristics of the causative agent].
In Zh Mikrobiol Epidemiol Immunobiol, 2014
GAS emm-type was determined by molecular-genetic methods, as well as the presence of bacteriophage integrases int2, int3, int4, int5, int6, int7, int49, bacteriophage toxins speA, speI, sla, speC/J, speL, speH, speC, ssa and speB gene present on the chromosomal DNA.
Galantamine for vascular cognitive impairment.
Oxford, United Kingdom. In Cochrane Database Syst Rev, 2012
Both trials had an overall low risk of bias.The GAL-INT-6 trial included 592 patients with vascular dementia diagnosed according to recognised criteria and patients with Alzheimer's disease and coincidental radiographic findings of cerebrovascular disease.
Clinical and laboratory aspects of Ro/SSA-52 autoantibodies.
Milano, Italy. In Autoimmun Rev, 2011
Isolated congenital complete atrioventricular block (CAVB) shows a close association with maternal anti-Ro/SSA and anti-La/SSB antibodies; the highest relative risks of CAVB are seen in offspring of mothers with antibodies against 52-kDa Ro and 48-kDa La proteins.
Management of mixed dementia.
Genève, Switzerland. In Drugs Aging, 2010
There is only one original randomized clinical trial on (acetyl)cholinesterase inhibitor therapy (GAL-INT-6, galantamine) for MD; the other studies are post hoc analyses of AD trial subgroups (AD2000, donepezil) or of VaD trial subgroups (VantagE, rivastigmine).