Amyotrophic lateral sclerosis--a model of corticofugal axonal spread.
Ulm, Germany. In Nat Rev Neurol, Dec 2013
The pathological process underlying amyotrophic lateral sclerosis (ALS) is associated with the formation of cytoplasmic inclusions consisting mainly of phosphorylated 43-kDa transactive response DNA-binding protein (pTDP-43), which plays an essential part in the pathogenesis of ALS.
Kanazawa, Japan. In Brain Nerve, Apr 2013
Moreover, a recent study suggested the presence of autoantibodies to a 43-kDa muscle protein in patients with inclusion body myositis.
Poxvirus cell entry: how many proteins does it take?
Bethesda, United States. In Viruses, 2012
Regardless of the pathway or whether the MV or EV mediates infection, fusion is dependent on 11 to 12 non-glycosylated, transmembrane proteins ranging in size from 4- to 43-kDa that are associated in a complex.