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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Interferon induced transmembrane protein 3

18 U, MILI, Interferon-inducible, mIL-1, IFITM3, Piwil2
Top mentioned proteins: Piwi, CAN, ACID, HAD, IL-1beta
Papers using 18 U antibodies
Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation
Supplier
Kotake Yashige et al., In Journal of Clinical Biochemistry and Nutrition, 2004
... Water was purified by distillation and passing through a Mili-Q system (Milipore Corp ...
Papers on 18 U
Interferon-inducible GTPases in cell autonomous and innate immunity.
Review
New
Broz et al., Basel, Switzerland. In Cell Microbiol, Feb 2016
Detection and clearance of invading pathogens requires a coordinated response of the adaptive and innate immune system.
Identification of cell-specific targets of sumoylation during mouse spermatogenesis.
New
Vigodner et al., Charlottesville, United States. In Reproduction, Feb 2016
The analyses confirmed the cell-specific sumoylation and/or SUMO interaction of several novel, previously uncharacterized SUMO targets such as CDK1, RNAP II, CDC5, MILI, DDX4, TDP-43, and STK31.
PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway.
New
Pillai et al., Grenoble, France. In Mol Cell, Feb 2016
Here we demonstrate that endonucleolytic slicing of a transcript by the cytosolic mouse PIWI protein MILI acts as a trigger to initiate its further 5'→3' processing into non-overlapping fragments.
Sodium orthovanadate induces the apoptosis of SH-SY5Y cells by inhibiting PIWIL2.
New
Tong et al., Shenyang, China. In Mol Med Report, Jan 2016
The high expression of PIWIL2 contributed to the resistance effect of cisplatin in colon cancer cells, and the knockout of the PIWIL2 gene reduced the aggressive nature and malignant degree of colon cancer cells.
Increased levels of interferon-inducible protein 10 (IP-10) in 22q11.2 Deletion Syndrome.
New
Abrahamsen et al., Oslo, Norway. In Scand J Immunol, Jan 2016
Interferon-inducible protein 10 (IP-10) was also measured by ELISA to confirm the multiplex results.
Mice lack of LRG-47 display the attenuated outcome of infection with Schistosoma japonicum.
New
Ji et al., Nanjing, China. In Parasitol Res, Jan 2016
UNASSIGNED: Interferon-inducible GTPase LRG-47 (also named immune-related GTPase M, Irgm1) is a member of the p47 GTPase family that has been shown to regulate host resistance to intracellular pathogens.
Cancer/testis antigens trigger epithelial-mesenchymal transition and genesis of cancer stem-like cells.
Review
Zhou et al., Suzhou, China. In Curr Pharm Des, 2014
The can cer-testis antigens, such as SSX, MAGE-D4B, CAGE, piwil2, and CT45A1, upregulate EMT and metastatic genes, promoting EMT and tumor dissemination.
Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications.
Review
Yount et al., Columbus, United States. In Future Microbiol, 2013
IFITM3 restricts cellular infection by multiple important viral pathogens, and is particularly critical for the innate immune response against influenza virus.
Differential L1 regulation in pluripotent stem cells of humans and apes.
Impact
Gage et al., Los Angeles, United States. In Nature, 2013
Decreased levels of L1-restricting factors APOBEC3B (also known as A3B) and PIWIL2 (ref.
An updated systematic review of the role of host genetics in susceptibility to influenza.
Review
Baillie et al., Vietnam. In Influenza Other Respi Viruses, 2013
One study does however present convincing functional evidence for an important role for IFITM3 in susceptibility to severe influenza in mice, and some evidence that this may also be important in human A/H1N1/pdm2009 infection.
[Perinatal innate immune activation and neuropsychological development].
Review
Nagai, In Nihon Shinkei Seishin Yakurigaku Zasshi, 2013
Neonatal treatment of mice with polyI:C, an inducer of innate immune responses via toll-like receptor 3, caused a significant increase in interferon-induced transmembrane protein 3 (IFITM3) levels in the astrocytes of the hippocampus, which resulted in long-lasting brain dysfunction, including cognitive and emotional impairments as well as a deficit in depolarization-evoked glutamate release in the hippocampus in adulthood.
Enhanced survival of lung tissue-resident memory CD8⁺ T cells during infection with influenza virus due to selective expression of IFITM3.
Impact
Villadangos et al., Melbourne, Australia. In Nat Immunol, 2013
Here we found that lung T(RM) cells selectively maintained expression of the interferon-induced transmembrane protein IFITM3, a protein that confers broad resistance to viral infection.
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.
Impact
Cheng et al., Los Angeles, United States. In Immunity, 2013
Interferons (IFN) are essential antiviral cytokines that establish the cellular antiviral state through upregulation of hundreds of interferon-stimulated genes (ISGs), most of which have uncharacterized functions and mechanisms.
Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis.
GeneRIF
Mourelatos et al., Philadelphia, United States. In Nat Struct Mol Biol, 2012
characterize the genome-wide target RNA repertoire of Mili (Piwil2) and Miwi (Piwil1), two Piwi proteins expressed in postnatal testis
S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus.
GeneRIF
Hang et al., New York City, United States. In J Biol Chem, 2012
S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus.
Interferon-inducible effector mechanisms in cell-autonomous immunity.
Review
Impact
MacMicking, New Haven, United States. In Nat Rev Immunol, 2012
Interferons (IFNs) induce the expression of hundreds of genes as part of an elaborate antimicrobial programme designed to combat infection in all nucleated cells - a process termed cell-autonomous immunity.
IFITM3 restricts the morbidity and mortality associated with influenza.
Impact
GeneRIF
Kellam et al., Sanger, United States. In Nature, 2012
IFITM3 is essential for defending the host against influenza A virus in vivo; mice lacking Ifitm3 display fulminant viral pneumonia when challenged with a normally low-pathogenicity influenza virus, mirroring the destruction inflicted by the highly pathogenic 1918 'Spanish' influenza
Piwil2 suppresses p53 by inducing phosphorylation of signal transducer and activator of transcription 3 in tumor cells.
GeneRIF
Ma et al., Chengdu, China. In Plos One, 2011
Piwil2 plays a role in anti-apoptosis in tumor cells possessing P53 as a positive regulator of STAT3 signaling pathway.
Germline stem cell gene PIWIL2 mediates DNA repair through relaxation of chromatin.
GeneRIF
Gao et al., Columbus, United States. In Plos One, 2010
a new role for Piwil2 in DNA repair
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