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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Phosphohistidine phosphatase 1

14-kDa phosphohistidine phosphatase, PHPT1, phosphohistidine phosphatase, Phosphohistidine phosphatase 1, phosphohistidine phosphatase PHPT1, PHP14
PHPT1 is an EDTA-insensitive phosphohistidine phosphatase that catalyzes the dephosphorylation of phosphopeptide I (Ek et al., 2002 [PubMed 12383260]).[supplied by OMIM, Mar 2008] (from NCBI)
Papers on 14-kDa phosphohistidine phosphatase
Influence of protein histidine phosphatase overexpression and down-regulation on human umbilical-vein endothelial cell viability.
Krieglstein et al., Münster, Germany. In Cell Biol Int, 2012
Overexpression of PHP by the use of a plasmid vector, pIRES2-AcGFP1-PHP, induced apoptosis in HUVEC
Clinical significance of PHPT1 protein expression in lung cancer.
Gu et al., Beijing, China. In Chin Med J (engl), 2010
Significantly higher expression levels of PHPT1 protein were found in lung cancer samples than in normal tissues adjacent to lung cancer.
Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells.
Kowluru et al., Detroit, United States. In Am J Physiol Endocrinol Metab, 2010
these data implicate regulatory roles for PHPT1 in a G protein-sensitive step involved in nutrient-induced insulin secretion
14-kDa phosphohistidine phosphatase and its role in human lung cancer cell migration and invasion.
He et al., Beijing, China. In Lung Cancer, 2010
These results demonstrate for the first time that PHP14 may be functionally important in lung cancer cell migration and the invasion of lung cancer cells, mediated partly through modulation of actin cytoskeleton rearrangement.
Role of protein histidine phosphatase for viability of neuronal cells.
Krieglstein et al., Münster, Germany. In Brain Res, 2009
results suggest that an increased activity of protein histidine phosphatase (PHP) impairs neuron cellular function whereas downregulation of PHP does not
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