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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

14-3-3 protein beta
Papers on 14-3-3 protein beta
Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion.
New
Impact
Wolchok et al., New York City, United States. In Immunity, Feb 2016
Using a system in which precursor frequency can be manipulated in a murine melanoma model, we demonstrated that the clonal abundance of CD4(+) T cells specific for self-tumor antigen positively correlated with antitumor efficacy.
HIV and Tfh Cells: Circulating New Ideas to Identify and Protect.
New
Impact
Silvestri et al., Atlanta, United States. In Immunity, Feb 2016
(2016) report that circulating IL-21-producing CD4(+) T cells are phenotypically, transcriptionally, and functionally similar to lymphoid Tfh cells and that such HIV-specific Tfh cells were increased in RV144 trial vaccine recipients.
Myelopoiesis Reloaded: Single-Cell Transcriptomics Leads the Way.
New
Impact
Beyer et al., Bonn, Germany. In Immunity, Feb 2016
In a recent issue of Cell, Paul et al.
Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.
New
Impact
Marazzi et al., New York City, United States. In Immunity, Feb 2016
Inhibition of host factors co-opted during active infection is a strategy hosts use to suppress viral replication and a potential pan-antiviral therapy.
Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration.
New
Impact
Legler et al., Kreuzlingen, Switzerland. In Immunity, Feb 2016
Here, we showed that different inflammatory stimuli provoked oligomerization of the chemokine receptor CCR7, enabling human dendritic cells and T cell subpopulations to process guidance cues not only through classical G protein-dependent signaling but also by integrating an oligomer-dependent Src kinase signaling pathway.
Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
GeneRIF
Reue et al., Los Angeles, United States. In J Biol Chem, 2010
Studies suggest that insulin may modulate the cellular function of lipin-1 by regulating its subcellular localization through interactions with 14-3-3 proteins.
14-3-3beta-Rac1-p21 activated kinase signaling regulates Akt1-mediated cytoskeletal organization, lamellipodia formation and fibronectin matrix assembly.
GeneRIF
Byzova et al., Cleveland, United States. In J Cell Physiol, 2009
Akt1 is necessary for the growth factor stimulated activation of 14-3-3beta-Rac1-p21 activated kinase (Pak) pathway in endothelial cells and fibroblasts.
An obligatory heterodimer of 14-3-3beta and 14-3-3epsilon is required for aldosterone regulation of the epithelial sodium channel.
GeneRIF
Frizzell et al., Pittsburgh, United States. In J Biol Chem, 2008
aldosterone-induced 14-3-3 isoforms, beta and epsilon, interact with phospho-Nedd4-2 as an obligatory heterodimer, blocking its interaction with ENaC and thereby increasing apical ENaC density and sodium transport.
A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasis.
GeneRIF
Tashiro et al., Noda, Japan. In J Biol Chem, 2008
FBI1 and 14-3-3beta were presented on the MKP-1 promoter. These results indicate that FBI1 promotes sustained ERK1/2 activation through repression of MKP-1 transcription, resulting in promotion of tumorigenicity and metastasis.
Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins.
GeneRIF
Chavakis et al., Bethesda, United States. In Blood, 2008
Cbl-b deficiency. Cbl-b deficiency resulted in increased phosphorylation of T758 in the beta2-chain of LFA-1 and thereby in enhanced association of 14-3-3beta protein with the beta2-chain
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